Elevated Lipoprotein(a) Independently Increases Risk for Short-Term Atherosclerotic Cardiovascular Events in Machine Learning Predictive Models

Lp(a) is a significant predictor of short-term ASCVD risk. Assessing Lp(a) and imminent ASCVD risk may assist in identifying patients who may benefit from escalation of preventative therapies.

Authors

Rajesh Dash (ORCID: https://orcid.org/0000-0002-2499-6389)
Fátima Rodríguez (ORCID: https://orcid.org/0000-0002-5226-0723)
Abha Khandelwal (ORCID: https://orcid.org/0000-0002-5190-3467)
Anthony Lozama
Brynn Kron
Shriram Nallamshetty (ORCID: https://orcid.org/0000-0002-1256-5741)
Andrew Ward (ORCID: https://orcid.org/0000-0002-4692-1126)
Alexander T. Sandhu (ORCID: https://orcid.org/0000-0003-3208-1143)

Institutions

VA Palo Alto Health Care System (US)
Novartis (United States) (US)
Box (United States) (US)
Stanford Medicine (US)

Publication Details

Journal: JACC Advances
Published: 2025-10-25
DOI: https://doi.org/10.1016/j.jacadv.2025.102253
Primary Topic: Lipoproteins and Cardiovascular Health
Type: article
Field-Weighted Citation Impact: 0.00

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article

Elevated Lipoprotein(a) Independently Increases Risk for Short-Term Atherosclerotic Cardiovascular Events in Machine Learning Predictive Models

Rajesh Dash, Fátima Rodríguez, Abha Khandelwal, Anthony Lozama et al.

Oct 25, 2025

JACC Advances

Lipoproteins and Cardiovascular Health

article

Elevated Lipoprotein(a) Independently Increases Risk for Short-Term Atherosclerotic Cardiovascular Events in Machine Learning Predictive Models

Rajesh Dash, Fátima Rodríguez, Abha Khandelwal, Anthony Lozama, Brynn Kron, Shriram Nallamshetty, Andrew Ward, Alexander T. Sandhu

October 25, 2025article en

Abstract

Lp(a) is a significant predictor of short-term ASCVD risk. Assessing Lp(a) and imminent ASCVD risk may assist in identifying patients who may benefit from escalation of preventative therapies.

JACC AdvancesVol. 4(11)

VA Palo Alto Health Care System (US), Novartis (United States) (US), Box (United States) (US), Stanford Medicine (US)

Openalex Percentile: Top 52%

Lipoproteins and Cardiovascular Health

DOI Open Access PDF OpenAlex

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