Higher Circulating Testosterone Linked to Higher CAD Risk in Men: Mendelian Randomization and Survival Analyses
These data suggest that increased testosterone may increase the risk of cardiovascular disease and that this safety concern should be a focus in future clinical trials for testosterone supplementation.
Authors
- Ken K. Ong (ORCID: https://orcid.org/0000-0003-4689-7530)
- John R. B. Perry (ORCID: https://orcid.org/0000-0001-6483-3771)
- Felix R. Day (ORCID: https://orcid.org/0000-0003-3789-7651)
- Adam S. Butterworth (ORCID: https://orcid.org/0000-0002-6915-9015)
- Nicholas J. Wareham (ORCID: https://orcid.org/0000-0003-1422-2993)
- Emily J Morbey
Institutions
- University of Cambridge (GB)
- Royal Papworth Hospital (GB)
- Victor (Japan) (JP)
- British Heart Foundation (GB)
- Cambridge School (PT)
- Primary Health Care (QA)
- Health Data Research UK (GB)
- MRC Epidemiology Unit (GB)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1210/clinem/dgaf582
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29