A systematic review of vision and vision-language foundation models in ophthalmology
Vision and vision-language foundation models in ophthalmology show significant potential for advancing diagnostic accuracy and treatment strategies, particularly in retinal diseases, glaucoma, and ocular oncology. However, challenges such as data quality, transparency, and ethical considerations must be addressed. Future research should focus on refining model performance, improving interpretability and generalizability, and exploring strategies for integrating these models into routine clinical practice to maximize their impact in clinical ophthalmology.
Authors
- Zongyuan Ge (ORCID: https://orcid.org/0000-0002-5880-8673)
- Andrzej E. Grzybowski (ORCID: https://orcid.org/0000-0002-3724-2391)
- Kai Jin (ORCID: https://orcid.org/0000-0003-4369-2417)
- Danli Shi (ORCID: https://orcid.org/0000-0001-6094-137X)
- Kelvin Zhenghao Li (ORCID: https://orcid.org/0000-0002-9993-5118)
- Yu Tao (ORCID: https://orcid.org/0000-0002-5688-0073)
- Gui‐Shuang Ying (ORCID: https://orcid.org/0000-0002-5752-1355)
- Polat Göktaş (ORCID: https://orcid.org/0000-0001-7183-6890)
- Yukun Zhou (ORCID: https://orcid.org/0000-0002-0840-6422)
- Meng Wang (ORCID: https://orcid.org/0000-0001-7882-1747)
Institutions
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- Sabancı Üniversitesi (TR)
- Hong Kong Polytechnic University (HK)
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Hawassa University (ET)
- Tan Tock Seng Hospital (SG)
- Moorfields Eye Hospital (GB)
- Second Affiliated Hospital of Zhejiang University (CN)
- Smith-Kettlewell Eye Research Institute (US)
- University College London (GB)
- University of Warmia and Mazury in Olsztyn (PL)
- Monash University (AU)
- Zhejiang University (CN)
- University of Pennsylvania (US)
Publication Details
- Journal
- Advances in Ophthalmology Practice and Research
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.aopr.2025.10.004
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 0.00