Causal nonlinear dose response analysis of donor–recipient predicted heart mass ratio

Accurately modeling the effect of donor-recipient heart size matching is necessary to inform the decision of whether to accept or reject a donor organ. We found that heart undersizing confers an increased risk of mortality. We fail to find large changes in the slope of the effect at any particular PHM ratio cutoff.

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Publication Details

Journal
JHLT Open
Published
2025-10-25
DOI
https://doi.org/10.1016/j.jhlto.2025.100418
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Causal nonlinear dose response analysis of donor–recipient predicted heart mass ratio

Maria Currie, Nataliya Bahatyrevich, Katharine Casselman Pines, Matthew Leipzig et al.
JHLT Open
Transplantation: Methods and Outcomes
article

Causal nonlinear dose response analysis of donor–recipient predicted heart mass ratio

Maria Currie, Nataliya Bahatyrevich, Katharine Casselman Pines, Matthew Leipzig, Reid Dale
article en

Abstract

Accurately modeling the effect of donor-recipient heart size matching is necessary to inform the decision of whether to accept or reject a donor organ. We found that heart undersizing confers an increased risk of mortality. We fail to find large changes in the slope of the effect at any particular PHM ratio cutoff.

JHLT OpenVol. 11
University of California, Davis (US), Stanford University (US)
National Heart, Lung, and Blood Institute
Openalex Percentile: Top 52%
Transplantation: Methods and Outcomes
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