Effect of treat-to-target strategies on maternal and neonatal outcomes of rheumatoid arthritis: a multicentre real-world ANSWER cohort study
T2T management, including selective continuation of bDMARDs, was associated with favourable maternal disease control and reassuring pregnancy outcomes. Although the absence of long-term follow-up is a limitation, these findings provide real-world evidence supporting this approach. Larger prospective studies are required to confirm maternal and neonatal safety beyond the early postpartum.
Authors
- Hideki Amuro (ORCID: https://orcid.org/0000-0002-7299-2884)
- Sho Sendo (ORCID: https://orcid.org/0000-0002-7193-341X)
- Yuichi Maeda (ORCID: https://orcid.org/0000-0002-6831-8205)
- Kosuke Ebina (ORCID: https://orcid.org/0000-0002-2426-1024)
- Tôru Hirano (ORCID: https://orcid.org/0000-0001-8467-3154)
- Motomu Hashimoto (ORCID: https://orcid.org/0000-0002-9241-060X)
- Kosaku Murakami (ORCID: https://orcid.org/0000-0001-5981-4648)
- Tohru Takeuchi (ORCID: https://orcid.org/0000-0002-0065-929X)
- Natsuki Yamamoto
- Ayaka Yoshikawa (ORCID: https://orcid.org/0000-0002-1927-1295)
- Masaki Katayama
- Yonsu Son (ORCID: https://orcid.org/0000-0001-7244-7715)
- Ryota Hara (ORCID: https://orcid.org/0000-0001-8000-3196)
- Wataru Yamamoto (ORCID: https://orcid.org/0000-0002-0810-4221)
- Akira Onishi
- Eri Nakamura
- Kouichi Murata
Institutions
- Kansai Medical University (JP)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Kyoto University (JP)
- Osaka City University (JP)
- Nishinomiya Municipal Central Hospital (JP)
- Kurashiki Medical Center (JP)
- Osaka Red Cross Hospital (JP)
- Osaka University Hospital (JP)
- Osaka City University Hospital (JP)
- Nara Medical University (JP)
- Kobe University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1093/rheumatology/keaf558
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00