Artificial Enzymatic Electrochemistry

Artificial enzymatic electrochemistry has emerged as an effective method to extend the catalytic abilities of enzymes, further increasing selectivity and efficiency, while also addressing limitations with stability, substrate scope, and reaction scale. Bioelectrochemical methods are powerful analytical tools to understand and optimize the structure and function of artificial enzymes. However, advancements in this field are hindered by the challenges of practical implementation and insufficient foundational knowledge required for effective integration of biological and electrochemical techniques. This review aims to provide clear examples of artificial enzymatic electrochemistry with an emphasis on the techniques and data that can be obtained for each example. Additionally, we provide an overview of enzymatic electrochemistry experimental design to encourage the incorporation of these techniques into future enzymology research. The review concludes by discussing the outlook and perspective on future opportunities for development.