The Added Value of Genome-Wide Copy Numbers to Objectively Resolve Clonality of Multiple Tumors With Pulmonary Involvement and Ambiguous or Inconclusive Mutational Diagnosis
Genome-wide CNA analysis provides complementary information to resolve clonality of MCs with ambiguous mutational clonality status, enhancing clinical decision-making.
Authors
- Bauke Ylstra (ORCID: https://orcid.org/0000-0001-9479-3010)
- Jacqueline Egthuijsen
- Jurriaan Janssen (ORCID: https://orcid.org/0000-0003-2536-7864)
- Anke van den Berg (ORCID: https://orcid.org/0000-0002-8894-2638)
- José Carlos Machado (ORCID: https://orcid.org/0000-0003-4741-8415)
- Hendrik F. van Essen
- Albrecht Stenzinger (ORCID: https://orcid.org/0000-0003-1001-103X)
- Teodora Radonic (ORCID: https://orcid.org/0000-0002-6015-5202)
- Anabela Ferro (ORCID: https://orcid.org/0000-0001-6042-4591)
- Bárbara Andrade Barbosa (ORCID: https://orcid.org/0000-0001-6428-9147)
- Erik Thunnissen (ORCID: https://orcid.org/0000-0001-5355-8508)
- Tim R. Mocking (ORCID: https://orcid.org/0000-0001-9170-4131)
- Yongsoo Kim (ORCID: https://orcid.org/0000-0002-2995-2131)
- Paul P. Eijk
- Jose-Pedro Parracha de Matos
- Swip Draijer
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Universidade do Porto (PT)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Amsterdam University Medical Centers (NL)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- JTO Clinical and Research Reports
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.jtocrr.2025.100921
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amsterdam University Medical Centers