Radiological features of sinonasal NUT (nuclear protein in testis) carcinoma: case series and systematic review
Sinonasal NUT carcinoma demonstrates characteristic imaging features including predilection for ethmoid sinus and nasal cavity, heterogeneous enhancement, and extensive invasive/destructive changes with frequent orbital and intracranial extension. While these features overlap with other sinonasal malignancies, recognition of these patterns may facilitate earlier diagnosis of this rare but highly aggressive tumor.
Authors
- Hiroya Ojiri (ORCID: https://orcid.org/0000-0002-5573-6299)
- Shotaro Naganawa (ORCID: https://orcid.org/0000-0001-8487-4853)
- Yoko Tabuchi
- Sumiko Okubo
- Akira Baba (ORCID: https://orcid.org/0000-0001-6913-5307)
- Satoshi Matsushima (ORCID: https://orcid.org/0000-0002-9940-5205)
- Hideomi Yamauchi (ORCID: https://orcid.org/0000-0003-4211-7568)
- Shohei Kiso
- Ashok Srinivasan (ORCID: https://orcid.org/0000-0002-4400-1959)
- Kensaku Mori (ORCID: https://orcid.org/0000-0002-2599-0245)
- Makoto Hinotsume
Institutions
- Jikei University School of Medicine (JP)
- University of Michigan (US)
- University of California Davis Medical Center (US)
- Japanese Foundation For Cancer Research (JP)
Publication Details
- Journal
- Japanese Journal of Radiology
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1007/s11604-025-01893-4
- Primary Topic
- Protein Degradation and Inhibitors
- Type
- article
- Field-Weighted Citation Impact
- 0.00