Objective evaluation of platelet-rich plasma mesotherapy on facial skin quality: An interim split-face analysis using an advanced imaging system

This study provides novel objective evidence that PRP mesotherapy significantly improves facial gloss, a key feature of healthy young skin. An exploratory trend toward pore reduction was also observed, although mechanistic interpretations remain hypothesized owing to the absence of biophysical and structural measurements. Moving beyond subjective assessments, these findings support the potential of PRP for enhancing facial brightness, smoothness, and overall skin quality. Further studies with larger cohorts, extended follow-ups, and multimodal evaluations are warranted to validate and expand upon these preliminary results.