Adjuvant Radiation Therapy in Breast Cancer Patients With Neurofibromatosis Type 1: Safety and Long-Term Outcomes
Adjuvant radiation therapy is safe and effective in NF1 patients with breast cancer, despite a notably high incidence of low-grade acute skin toxicity. No serious long-term toxicity or radiation-induced malignancy was observed. Modern dose-sparing techniques should be prioritized, and further prospective studies are needed to refine treatment approaches in this high-risk group.
Authors
- Youlia Kirova (ORCID: https://orcid.org/0000-0002-1795-7509)
- Pierre Loap (ORCID: https://orcid.org/0000-0001-8863-8110)
- Carla BENMATALLAH
Institutions
- Délégation Paris 5 (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Institut d'Imagerie Biomédicale (FR)
- Institut Curie (FR)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.adro.2025.101931
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 0.00