Optimizing Selection of Reactive versus Prophylactic Gastrostomy Tube Placement in Patients Treated with Radiation Therapy for Head and Neck Cancer
Among patients planned for head and neck RT using an rGT paradigm, we identified predictors of GT placement or excessive weight loss on-treatment and developed a predictive model of GT placement in this group. Identifying patients at high risk of substantial weight loss and/or GT placement during RT may optimize personalization of rGT versus pGT. External validation of this model's ability to predict patients at high risk of ultimately receiving rGT is warranted.
Authors
- C.M. Lanier (ORCID: https://orcid.org/0000-0003-0127-9253)
- Bart Frizzell (ORCID: https://orcid.org/0000-0003-0748-3896)
- Ji Hae Lee (ORCID: https://orcid.org/0000-0002-5132-1627)
- R.F. Shenker (ORCID: https://orcid.org/0000-0001-6552-6255)
- Ralph B. D’Agostino (ORCID: https://orcid.org/0000-0002-3550-8395)
- N. Razavian (ORCID: https://orcid.org/0000-0001-5746-9860)
- Sydney A. Smith (ORCID: https://orcid.org/0000-0001-6540-8179)
- Ryan T. Hughes (ORCID: https://orcid.org/0000-0003-1548-9753)
- Akshay Iyer (ORCID: https://orcid.org/0009-0001-5835-4747)
- Nicholas A. Gallardo
Institutions
- Intermountain Healthcare (US)
- Moffitt Cancer Center (US)
- Wake Forest University (US)
Publication Details
- Journal
- Advances in Radiation Oncology
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.adro.2025.101930
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Comprehensive Cancer Center at Wake Forest Baptist Medical Center
- National Institutes of Health
- National Cancer Institute