Prevalence and molecular epidemiology of optrA-positive Enterococcus in herders and yaks from high-altitude Tibet, China
The presence of optrA-positive Enterococcus in both human and animal populations in this high-altitude region underscores the role of human-animal interactions in AMR transmission. The increasing prevalence of resistant strains in yaks, coupled with genetic evidence of clonal expansion, highlights the need for a comprehensive One Health approach to AMR surveillance and mitigation in remote, high-altitude environments.
Authors
- Aoxiao Chen
- Zelin Yan (ORCID: https://orcid.org/0009-0008-8984-2031)
- Yang Wang (ORCID: https://orcid.org/0000-0002-5928-9377)
- Rong Zhang (ORCID: https://orcid.org/0000-0002-2174-7985)
- Hanyu Wang (ORCID: https://orcid.org/0000-0002-6923-680X)
- Xinyue Han
Institutions
- Tibet Autonomous Region People's Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- China Agricultural University (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.jgar.2025.10.016
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00