Metallomics dataset of clinical isolates of Klebsiella pneumoniae exposed to varying concentration of human plasma in Muller Hinton Broth

Multidrug-resistant <i>Klebsiella pneumoniae</i> (<i>K. pneumoniae</i>) is a leading cause of bloodstream bacterial infections. Upcoming studies indicate an increasing trend in the prevalence of MDR <i>K. pneumoniae</i>, especially among ICU patients, contributing to prolonged hospital stays due to limited treatment options and hence increased treatment costs, which demands a better understanding of survival mechanisms of pathogens in the bloodstream for devising improved novel therapeutic strategies. Intracellular metal ions dynamics plays an important role in the survival, virulence and interaction of bacteria within host environments. However, no study in this direction has been reported for <i>K. pneumoniae</i> to date. This dataset comprises Inductively Coupled Plasma Mass Spectrometry (ICP-MS) intracellular metal ion profile of 7 clinical and one ATCC strains of <i>K. pneumoniae</i> grown in varied concentrations of human plasma (h-plasma; 0, 5, 10, 25, 55, and 100 % (vol/vol)) supplemented Muller Hinton Broth (MHB) for 4 h (h). Based on bacterial growth, metal profile data was divided into two groups, i.e., h-plasma sensitive and insensitive strains. This data will be beneficial for extracting information to target metal-associated bacterial physiological processes for developing therapeutic interventions<i>.</i>