Depletion of myeloid-derived Zbtb46+ cells improves glycemic control in obesity via the DPP4/GLP-1 pathway
These findings uncover a novel, non-inflammatory role for ATDCs in glucose regulation via the DPP4/GLP-1/GLP-1R axis, positioning them as promising therapeutic targets for obesity and related metabolic diseases.
Authors
- Sooyoung Kim
- Shindy Soedono (ORCID: https://orcid.org/0000-0001-5252-893X)
- Sharlene Sharlene
- Jun Young Hong (ORCID: https://orcid.org/0000-0002-5257-6525)
- Ha Q. Vo (ORCID: https://orcid.org/0000-0002-7066-1467)
- Jiyeon Chang (ORCID: https://orcid.org/0000-0003-4490-5314)
- Kae Won Cho (ORCID: https://orcid.org/0000-0001-7512-6722)
- Princess Wendy Bayona
Institutions
- Yonsei University (KR)
- Soonchunhyang University (KR)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.jare.2025.10.032
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00