Paradoxical ileocecal perforation during early anti-tuberculosis therapy: A rare case report
This case highlights the importance of recognizing paradoxical reactions, such as intestinal perforation, as potential complications during the early phase of anti-tubercular therapy. Maintaining early vigilance and a high index of suspicion is essential for timely diagnosis and appropriate intervention. Clinicians should consider paradoxical perforation in patients who deteriorate shortly after initiating anti-TB treatment, even when adherence is confirmed. Early surgical intervention, guided by a high index of suspicion, is crucial to reducing morbidity and improving outcomes in intestinal tuberculosis.
Authors
- Binyam M Habte
- Solomon Abebe Yimer (ORCID: https://orcid.org/0000-0003-0959-3052)
- Yemiserach Kifle (ORCID: https://orcid.org/0009-0007-0073-1064)
- Esimael M Abdu
- Yoseph M Habte
- Makida M Habte
Institutions
- St. Paul's Hospital Millennium Medical College (ET)
- Addis Ababa University (ET)
- University of Gondar (ET)
Publication Details
- Journal
- International Journal of Surgery Case Reports
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.ijscr.2025.112100
- Primary Topic
- Diagnosis and treatment of tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00