The safety of pyrazinamide in pediatric drug-sensitive tuberculosis treatment: A real-world study
Real-world PZA dosage and duration in pediatric drug-sensitive TB frequently deviated from WHO guidelines. The initial two months of concomitant PZA use may warrant particular safety attention, especially in children on the enhanced combination regimen.
Authors
- Xin-Xin I. Zeng (ORCID: https://orcid.org/0000-0002-2707-7759)
- Xin Yu (ORCID: https://orcid.org/0000-0002-9072-6862)
- Bin Chen (ORCID: https://orcid.org/0000-0001-8690-1835)
- Juanjuan Liu
- Lisu Huang (ORCID: https://orcid.org/0000-0001-8193-7353)
- Aole Li
- Guangxu Yang (ORCID: https://orcid.org/0000-0001-9916-0765)
- Man Tian (ORCID: https://orcid.org/0000-0001-9857-5256)
- Xingyu Dong
- Haiyan Li (ORCID: https://orcid.org/0000-0003-2367-676X)
- Fei Wang (ORCID: https://orcid.org/0000-0003-3948-6899)
- Ping Liu (ORCID: https://orcid.org/0000-0002-2026-122X)
- Hao Yao (ORCID: https://orcid.org/0000-0001-6444-7758)
- Hongmei Xu (ORCID: https://orcid.org/0000-0003-2088-1960)
- Yuhang Wu (ORCID: https://orcid.org/0000-0002-4339-0753)
- Qingshan Cai (ORCID: https://orcid.org/0000-0002-2611-7640)
- Juan Ma
- Xianhui Zeng
- Qing Fang
Institutions
- Wenzhou Medical University (CN)
- Nanjing Children's Hospital (CN)
- Qinghai No.3 People's Hospital (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Ningbo No. 2 Hospital (CN)
- Shanghai Public Health Clinical Center (CN)
- Hainan Modern Women and Children's Hospital (CN)
- Children's Hospital of Zhejiang University (CN)
- Changchun Obstetrics and Gynecology Hospital (CN)
- Changchun 208 Hospital (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
- Hangzhou Red Cross Hospital (CN)
- Shanghai Clinical Research Center (CN)
- Children's Hospital of Chongqing Medical University (CN)
- The Fifth People’s Hospital of Suzhou (CN)
- Hainan Medical University (CN)
- Nanjing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Infection and Public Health
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.jiph.2025.103022
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40