Sensitive detection of bisulfite by a novel quinoxaline-based fluorescent probe and its applications in food detection and bioimaging
Bisulfite (HSO<sub>3</sub><sup>-</sup>) is a widely used food additive that plays a crucial role in many physiological processes. Nevertheless, excessive amounts of HSO<sub>3</sub><sup>-</sup> can bring about incalculable harm to human health. Hence, monitoring the residual HSO<sub>3</sub><sup>-</sup> in food samples is of utmost significance for human health. In this work, a ratiometric fluorescent probe (DPTI), derived from camphorquinone, was synthesized for detecting HSO<sub>3</sub><sup>-</sup>. This probe showed a colorimetric and fluorescence dual response to HSO<sub>3</sub><sup>-</sup> within 10 min, with high selectivity (LOD = 0.07 μM). In addition, the probe DPTI could be used for detecting HSO<sub>3</sub><sup>-</sup> content in food samples. Additionally, the good biocompatibility of probe DPTI makes it suitable for fluorescence bioimaging of HSO<sub>3</sub><sup>-</sup> in living organisms.
Authors
- Yueyin Liang
- Zhiyuan Meng (ORCID: https://orcid.org/0000-0003-4352-8561)
- Shuai Gong (ORCID: https://orcid.org/0000-0002-8812-2197)
- Yue Gu
- Lewei Gao
- Zhonglong Wang (ORCID: https://orcid.org/0000-0002-4283-6477)
- Shifa Wang (ORCID: https://orcid.org/0000-0001-8578-9845)
- Mengdi Zhao
- Yixin Yang (ORCID: https://orcid.org/0000-0001-5717-7075)
Institutions
- Nanjing Forestry University (CN)
Publication Details
- Journal
- Analytical Methods
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ay00699f
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00