Elevated gamma activity in left frontotemporal regions preceding sleep signals emotional arousal in Bipolar Disorders: Insights from a high-density EEG investigation
Our findings suggest an alteration in sleep onset, efficiency, and REM density in euthymic BD patients, in the context of a preserved sleep duration. Some of these changes may be associated with a neural signature of cortical arousal that influences sleep quality.
Authors
- Veronica Nisticò (ORCID: https://orcid.org/0000-0003-0249-9266)
- Maria Paola Canevini (ORCID: https://orcid.org/0000-0002-2292-4015)
- Caroline Zangani (ORCID: https://orcid.org/0000-0001-5883-0638)
- Francesco Donati (ORCID: https://orcid.org/0000-0001-9868-5439)
- Cecilia Casetta (ORCID: https://orcid.org/0000-0002-1980-3415)
- Armando D’Agostino (ORCID: https://orcid.org/0000-0002-2126-799X)
- Anna Castelnovo (ORCID: https://orcid.org/0000-0002-8875-9657)
- Renata del Giudice (ORCID: https://orcid.org/0000-0002-6037-662X)
- Elena Zambrelli (ORCID: https://orcid.org/0000-0001-8476-0960)
- Riccardo Stefanelli
- Maddalena Sala
- Claudio Sanguineti (ORCID: https://orcid.org/0009-0007-6836-1098)
Institutions
- AOL (United States) (US)
- University of Milan (IT)
- South London and Maudsley NHS Foundation Trust (GB)
- University of Pavia (IT)
- Warneford Hospital (GB)
- Laboratory for Biomedical Neurosciences (CH)
- Ente Ospedaliero Cantonale (CH)
- Ospedale San Paolo (IT)
- Oxford BioMedica (United Kingdom) (GB)
- Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
- University of Milano-Bicocca (IT)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-10-25
- DOI
- https://doi.org/10.1016/j.jad.2025.120517
- Primary Topic
- Bipolar Disorder and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute for Health and Care Research