Is it personality or genes? – A secondary analysis on a randomized controlled trial investigating responsiveness to placebo analgesia
Results did not support a role of a person's personality characteristics or genetic variations in predicting their responsiveness to placebo analgesia through learning mechanisms. The clinical relevance of predicting someone's responsiveness to placebo effects, therefore, requires careful reconsideration.
Authors
- Susan L. Kloet (ORCID: https://orcid.org/0000-0001-9189-0640)
- Rolf H. A. M. Vossen
- Oyin V. Leong
- Johan P. A. van Lennep
- Andrea W.M. Evers (ORCID: https://orcid.org/0000-0002-0090-5091)
- Tom Heyman (ORCID: https://orcid.org/0000-0003-0565-441X)
- Henriët van Middendorp (ORCID: https://orcid.org/0000-0003-4575-0895)
Institutions
- Leiden University (NL)
- University of Applied Sciences Leiden (NL)
- Leiden University Medical Center (NL)
- Erasmus MC (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- Scandinavian Journal of Pain
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1515/sjpain-2025-0029
- Primary Topic
- Pain Management and Placebo Effect
- Type
- article
- Field-Weighted Citation Impact
- 0.00