Chemical constituents from the tubers of <i>Pinellia pedatisecta</i> Schott
One undescribed five memebered cyclic compounds, 2,3-dimethyl-5-hydroxy-5-(2-oxopropyl)cyclopent-2-ene-1,4-dione (<b>1)</b>, together with twenty-three reported chemical constituents (<b>2</b>-<b>24</b>) were separated from the tubers of <i>Pinellia pedatisecta</i> Schott. The undescribed structure was elucidated by HRESIMS and NMR spectroscopic analyses. Additionally, the results of activity screening assay indicated that compounds <b>7</b> and compound <b>8</b> showed significant inhibitory activities against <i>α</i>-glucosidase with IC<sub>50</sub> values of 51.6 nmol/L and 13.43 nmol/L, respectively.
Authors
- Yingjie Niu (ORCID: https://orcid.org/0000-0003-1829-1718)
- Xiaoke Zheng (ORCID: https://orcid.org/0000-0003-3671-231X)
- Di Lu
- Yixin Zhao (ORCID: https://orcid.org/0000-0002-7856-2818)
- Lan Chen (ORCID: https://orcid.org/0000-0003-0157-1326)
- Xu Chen (ORCID: https://orcid.org/0000-0001-7007-3684)
- Yanling Liu (ORCID: https://orcid.org/0000-0002-2027-6464)
- Yan-Gang Cao (ORCID: https://orcid.org/0000-0002-6744-5974)
- Wei-Sheng Feng
- Fang-Ge Chi
- Bing-Xian Zhao
Institutions
- Ministry of Education (KR)
- Henan Bioengineering Technology Research Center (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1080/14786419.2025.2577775
- Citations
- 1
- Primary Topic
- Plant-based Medicinal Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56