Network of positive affect and depression in older adults

Depression in older adults poses significant health challenges, yet the protective role of positive affect remains understudied. This research examined the complex network of positive affect and depression in older adults using advanced network analysis techniques to identify potential targets for intervention. Bayesian Gaussian Graphical Models and Directed Acyclic Graph modelling were used to analyse associations between ten positive affect variables and depression. Exploratory and confirmatory network analyses ensured stability and node predictability quantified variable influence. Stepwise linear regression confirmed whether specific positive affective variables identified in the networks predicted lower depression scores. Enthusiasm emerged as a key ancestral node with the highest predictability ( R 2 = 0.65), initiating cascades of positive affect. A primary pathway to depression was identified through feeling active (strength = 1.00, direction = 0.79), with an indirect pathway from feeling enthusiastic via active (strength = 0.98, direction = 0.79) to depression (strength = 1.00, direction = 0.79). Confirmatory longitudinal analysis showed that feeling active and enthusiastic consistently predicted lower depression scores ( p < 0.001). The network structure remained stable across analyses. Enthusiasm was identified as a central catalyst in the positive affect network, revealing clear pathways through which positive affect may protect against depression in older adults. Enhancing enthusiastic and active emotional experiences emerged as potential effective, nonpharmacological strategies for preventing and treating depression in older adults. • Feeling active and enthusiastic associated with lower depression over time • Network analysis reveals affect pathways that protect against depression. • Interventions targeting enthusiasm may reduce late-life depression risk. • Positive affect cascades may offer non-pharmaceutical depression solutions. • Enthusiasm is central to the positive affect network in older adults.

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Publication Details

Journal
Journal of Affective Disorders
Published
2025-10-24
DOI
https://doi.org/10.1016/j.jad.2025.120529
Citations
1
Primary Topic
Mental Health Research Topics
Type
article
Field-Weighted Citation Impact
2.12
Controls
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article

Network of positive affect and depression in older adults

Patrick J. Leman, Henry Brodaty, Matti Cervin, Katya T. Numbers et al.
1 citations
Journal of Affective Disorders
Mental Health Research Topics
2.12
article

Network of positive affect and depression in older adults

Patrick J. Leman, Henry Brodaty, Matti Cervin, Katya T. Numbers, Perminder Singh Sachdev, Oleg N. Medvedev, Ella G. Hopkins
article en
1 citations

Abstract

Depression in older adults poses significant health challenges, yet the protective role of positive affect remains understudied. This research examined the complex network of positive affect and depression in older adults using advanced network analysis techniques to identify potential targets for intervention. Bayesian Gaussian Graphical Models and Directed Acyclic Graph modelling were used to analyse associations between ten positive affect variables and depression. Exploratory and confirmatory network analyses ensured stability and node predictability quantified variable influence. Stepwise linear regression confirmed whether specific positive affective variables identified in the networks predicted lower depression scores. Enthusiasm emerged as a key ancestral node with the highest predictability ( R 2 = 0.65), initiating cascades of positive affect. A primary pathway to depression was identified through feeling active (strength = 1.00, direction = 0.79), with an indirect pathway from feeling enthusiastic via active (strength = 0.98, direction = 0.79) to depression (strength = 1.00, direction = 0.79). Confirmatory longitudinal analysis showed that feeling active and enthusiastic consistently predicted lower depression scores ( p < 0.001). The network structure remained stable across analyses. Enthusiasm was identified as a central catalyst in the positive affect network, revealing clear pathways through which positive affect may protect against depression in older adults. Enhancing enthusiastic and active emotional experiences emerged as potential effective, nonpharmacological strategies for preventing and treating depression in older adults. • Feeling active and enthusiastic associated with lower depression over time • Network analysis reveals affect pathways that protect against depression. • Interventions targeting enthusiasm may reduce late-life depression risk. • Positive affect cascades may offer non-pharmaceutical depression solutions. • Enthusiasm is central to the positive affect network in older adults.

Journal of Affective DisordersVol. 394
Lund University (SE), UNSW Sydney (AU), University of Waikato (NZ)
Openalex Percentile: Top 10%
Mental Health Research Topics
2.12
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