Effect of a self-directed lifestyle-based weight management program among patients with comorbid COPD and sleep apnea: a secondary analysis of the INSIGHT COPD trial
Among patients with COPD and sleep apnea, a self-directed video-based weight management program led to favorable changes in 6MWT distance compared to usual care, though this did not meet the threshold of a clinically important improvement. However, fewer participants in the intervention group saw a decline in 6MWT distance, and more achieved meaningful weight loss. To effectively improve function in this population, additional interventions beyond self-directed weight management will be necessary.Clinical trial registered with www.clinicaltrials.gov (NCT02634268).
Authors
- Nadia N. Hansel (ORCID: https://orcid.org/0000-0002-8740-9751)
- Kirk Voelker
- M. Jeffery Mador (ORCID: https://orcid.org/0000-0003-2381-6339)
- Veeranna Maddipati (ORCID: https://orcid.org/0000-0003-3412-5824)
- Robert Plumley
- Loretta G. Que (ORCID: https://orcid.org/0000-0001-9188-9244)
- Igor Barjaktarević (ORCID: https://orcid.org/0000-0002-8096-0858)
- Christine Wendt (ORCID: https://orcid.org/0000-0002-7045-2366)
- Lucas M. Donovan (ORCID: https://orcid.org/0000-0001-8187-2641)
- Nicola A. Hanania (ORCID: https://orcid.org/0000-0003-3087-9530)
- A.G. Leonhard (ORCID: https://orcid.org/0009-0006-8565-8320)
- Scott Coggeshall
- Jun Ma (ORCID: https://orcid.org/0000-0001-7996-6454)
- MeiLan K. Han (ORCID: https://orcid.org/0000-0002-9095-4419)
- C.S. Pirozzi (ORCID: https://orcid.org/0000-0002-1533-1916)
- Emily Gleason (ORCID: https://orcid.org/0000-0001-8894-6471)
- Rebecca Bascom (ORCID: https://orcid.org/0000-0001-5875-3476)
- Stephen C. Lazarus (ORCID: https://orcid.org/0000-0002-3230-0556)
- Kaharu Sumino (ORCID: https://orcid.org/0000-0002-6214-2966)
- Frank C. Sciurba (ORCID: https://orcid.org/0000-0001-7468-2225)
- Marilyn L. Moy (ORCID: https://orcid.org/0000-0002-2471-9218)
- Barry J. Make (ORCID: https://orcid.org/0000-0003-4349-8745)
- Travis Hee Wai (ORCID: https://orcid.org/0000-0003-4016-8732)
- Paul Simonelli
- Sanjay Sethi (ORCID: https://orcid.org/0009-0001-5367-3730)
- Stephen R. Wisniewski (ORCID: https://orcid.org/0000-0002-3877-9860)
- Jerry A. Krishnan (ORCID: https://orcid.org/0000-0001-5525-4778)
- David H. Au (ORCID: https://orcid.org/0000-0001-8207-4975)
- Margaret P. Collins
- Alejandro P. Comellas (ORCID: https://orcid.org/0000-0003-1521-7520)
- Jessica M. Bon (ORCID: https://orcid.org/0000-0002-4336-3835)
- Robert M. Reed (ORCID: https://orcid.org/0000-0002-4681-7070)
- Anupama Tiwari (ORCID: https://orcid.org/0000-0003-1569-5354)
- Charlene McEvoy (ORCID: https://orcid.org/0000-0002-2813-9106)
- Catherine A. Meldrum
- Mark Millard
- Philip T. Diaz
- Laura C. Feemster
Institutions
- University of Iowa (US)
- University of Maryland, Baltimore (US)
- Geisinger Medical Center (US)
- University of Minnesota (US)
- Harvard University (US)
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- University of Pittsburgh (US)
- Duke University (US)
- University of California, San Francisco (US)
- Baylor College of Medicine (US)
- East Carolina University (US)
- University of Washington (US)
- Washington University in St. Louis (US)
- University of Utah (US)
- Johns Hopkins Medicine (US)
- Sinai Hospital (US)
- VA Boston Healthcare System (US)
- Baylor University Medical Center (US)
- University of California System (US)
- National Jewish Health (US)
- University of Illinois Chicago (US)
- University of Chicago (US)
- Sarasota Memorial Health Care System (US)
- VA Puget Sound Health Care System (US)
- Michigan United (US)
- Michigan Medicine (US)
- Minneapolis VA Health Care System (US)
- Sarasota Memorial Hospital (US)
- Pulmonary and Allergy Associates (US)
- Duke Medical Center (US)
- Office of Patient Care Services (US)
- Jacobs Institute (US)
- Department of Public Health (MM)
- Wake Forest University (US)
- The Ohio State University (US)
- HealthPartners (US)
- Geisinger Health System (US)
- University at Buffalo, State University of New York (US)
- Albany Medical Center Hospital (US)
- Penn State Milton S. Hershey Medical Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Annals of the American Thoracic Society
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1513/annalsats.202504-410oc
- Primary Topic
- Health and Wellbeing Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00