Postpartum pulmonary micronodules and thyroid cystic nodules in a COVID-19 vaccinated patient: A CARE-compliant case report

This case suggests prepregnancy vaccine immune imprinting may become activated under gestational stress, potentially triggering subclinical inflammation via the hypothalamic-pituitary-adrenal axis-gut microbiota-cytokine network. Consequently, we propose the "V-SLAM" clinical framework (vaccine history/stress biomarkers/lifestyle factors/autoimmunity screening/multidisciplinary consultation), emphasizing the integration of vaccination records and psychological resilience assessment into preconception counseling, with cross-pregnancy immune-metabolic monitoring for high-risk women.