Trends and characteristics during 17 years of naloxone distribution and administration through an overdose prevention program in Pittsburgh, Pennsylvania
While state legislation created the environment for expansion, reaching previously underserved communities required intentional new programmatic development and outreach. Long-term consistency of <2 doses per ORE, high survival rate, and robust utilization all lend confidence in prioritizing naloxone distribution directly to people who use drugs and their social networks. Trial registration: This investigation was pre-registered https://osf.io/b2f4h.
Authors
- Dorothy Chang
- Eliza Wheeler (ORCID: https://orcid.org/0000-0002-6643-0607)
- Alice Bell
- Jana McAninch
- Nabarun Dasgupta (ORCID: https://orcid.org/0000-0002-4098-605X)
- Maya Doe-Simkins
- Zachary Dezman (ORCID: https://orcid.org/0000-0001-6405-724X)
- Summer Barlow
- Adams L. Sibley (ORCID: https://orcid.org/0000-0001-5073-8677)
- Amy E. Seitz (ORCID: https://orcid.org/0000-0001-7417-145X)
- Maryalice Nocera
- Malcolm Visnich
Institutions
- University of North Carolina at Chapel Hill (US)
- United States Food and Drug Administration (US)
- Point Park University (US)
- School Based Health Alliance (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1371/journal.pone.0315026
- Citations
- 1
- Primary Topic
- Opioid Use Disorder Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.88