Bmi1 represses HLF to drive the formation and development of intrahepatic cholangiocarcinoma
These findings revealed the molecular mechanism through which Bmi1 promotes ICC formation and development and uncovered the role of HLF as a tumour suppressor in ICC.
Authors
- Ruitao Long
- Hua Wu (ORCID: https://orcid.org/0000-0003-1802-1363)
- Feng Ye (ORCID: https://orcid.org/0000-0002-6749-0417)
- Jun Guo (ORCID: https://orcid.org/0000-0002-8169-3034)
- Chuanrui Xu (ORCID: https://orcid.org/0000-0003-3225-4083)
- Xue Shi (ORCID: https://orcid.org/0000-0001-6293-8991)
- Yan Sun
Institutions
- Tongren University (CN)
- Central Hospital of Wuhan (CN)
- Tongji Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1038/s41416-025-03234-8
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00