Commensal dysbiosis promotes the development of colorectal cancer liver Metastasis via the C–C chemokine ligand 6/C–C chemokine receptor 1 axis
Commensal dysbiosis could promote CRLM development via CCL6/CCR1 signaling. Targeting this signaling axis could be an effective method to inhibit CRLM by regulating the TME.
Authors
- Yunsong Chen (ORCID: https://orcid.org/0000-0003-3799-0071)
- Mingming Li (ORCID: https://orcid.org/0000-0003-0621-6227)
- Zhicheng Sun (ORCID: https://orcid.org/0009-0009-0504-4807)
- Zhongchao Li (ORCID: https://orcid.org/0000-0002-3082-1163)
- Zhibin Chang
- Lei Zhao (ORCID: https://orcid.org/0000-0002-6824-6459)
- Yue Yang (ORCID: https://orcid.org/0000-0002-8270-9464)
Institutions
- Xinjiang Medical University (CN)
- Shandong University (CN)
- Shandong Tumor Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Cancer Research and Therapeutics
- Published
- 2025-10-14
- DOI
- https://doi.org/10.4103/jcrt.jcrt_1957_24
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00