Lipid raft proteomics identify endothelial myosin-9 (MYH9) as a regulator of low-density lipoprotein transcytosis and atherosclerosis
Lipid raft proteomics identified MYH9 as a regulator of LDL transcytosis. MYH9 is required for endothelial LDL exocytosis and contributes to early atherosclerosis.
Authors
- Myron I. Cybulsky (ORCID: https://orcid.org/0000-0002-1696-2867)
- Yafeng Lyu (ORCID: https://orcid.org/0000-0002-0620-574X)
- Warren L. Lee (ORCID: https://orcid.org/0000-0002-1788-6587)
- Ying Wang (ORCID: https://orcid.org/0000-0002-1444-5778)
- Erika Jang (ORCID: https://orcid.org/0000-0002-2650-5037)
- Changsen Wang
- G. Y. Wen
- Wan-Ling Cheng (ORCID: https://orcid.org/0000-0001-9837-9458)
- Andria Henry (ORCID: https://orcid.org/0009-0007-9264-0310)
- Tse Wing Winnie Ho (ORCID: https://orcid.org/0000-0003-4465-7859)
- Casey E. Romanoski (ORCID: https://orcid.org/0000-0002-0149-225X)
- Siavash Ghaffari (ORCID: https://orcid.org/0000-0002-8190-5674)
- Kuiru Wei
Institutions
- St. Michael's Hospital (CA)
- University of Arizona (US)
- University of British Columbia (CA)
- University of Toronto (CA)
- Toronto General Hospital (CA)
- St Michael’s Hospital (IE)
- Dermatology Research Center (US)
- Toronto General Hospital Research Institute
Publication Details
- Journal
- Proceedings of the National Academy of Sciences
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1073/pnas.2509315122
- Primary Topic
- Caveolin-1 and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00