Immunological parameters in serous catarrhal inflammation of the udder in lactating cows

The aim of this study is to investigate the immunological parameters of blood in lactating cows with serous-catarrhal mastitis to identify the pathogenetic mechanisms of the disease. The research was carried out in autumn in one of the livestock farms of the Amur region. The object of the study was lactating cows of Holstein breed at 2-4 months of lactation. Groups of cows were formed by 10 animals in each: control (healthy) and experimental (sick with serous catarrhal mastitis). The inflammatory process in the mammary gland of lactating cows was caused by tissue damage and complicated by opportunistic microflora. Protein metabolism disorders (hypoalbuminemia, dysproteinemia) and signs of haemoconcentration (increased haematocrit and haemoglobin, erythrocytosis) were observed in sick animals. Conditionally pathogenic microflora and products of inflammation in the mammary gland stimulated cellular and humoral immunity.