Exercise-induced alleviation of memory impairment in aged mice with neuroinflammation is linked with modulation of mitochondrial homeostasis in the hippocampus
our results provide the first evidence that exercise can protect cognitive function in the context of neuroinflammation in the aged hippocampus, suggesting that this effect may be associated with the improvement of mitochondrial homeostasis.
Authors
- Shan-Yao Pan
- Yaping Huai (ORCID: https://orcid.org/0000-0002-5379-2940)
- Gang Zhao (ORCID: https://orcid.org/0000-0003-2612-3052)
- Zheng‐Hong Qin
- Yiqing Lu (ORCID: https://orcid.org/0000-0003-3229-419X)
- Li Luo (ORCID: https://orcid.org/0000-0002-0536-0481)
- Jiaqi Zhou (ORCID: https://orcid.org/0000-0002-9285-8914)
- Peng Li (ORCID: https://orcid.org/0000-0003-2030-1807)
- Yuanyuan Qin (ORCID: https://orcid.org/0000-0003-0482-4632)
- Chong Hyun Han
- Xuewei Cao
- Zhi Jiang
- Bo Liao (ORCID: https://orcid.org/0000-0002-0666-4882)
- Nan Wang (ORCID: https://orcid.org/0009-0003-9735-4314)
Institutions
- Soochow University (CN)
- Longgang Central Hospital (CN)
- Suzhou Research Institute (CN)
- Suzhou Traditional Chinese Medicine Hospital (CN)
- Suzhou Vocational Health College (CN)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-10-23
- DOI
- https://doi.org/10.1093/gerona/glaf233
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00