Comparative evaluation of normal tissue objective functions in robotic radiosurgery planning for solitary brain tumors
NTO optimization presents a viable option to the Auto-shells method for CyberKnife treatment of brain tumors. By reducing healthy brain tissue exposure without increasing monitor units, it enhances dose-sparing efficiency. However, maintaining optimal conformity remains an important issue, highlighting the trade-offs between precision and tissue preservation.
Authors
- Martin Köcher (ORCID: https://orcid.org/0000-0002-5674-9227)
- Daniel Rueß (ORCID: https://orcid.org/0000-0003-1811-5132)
- Michael Judge
- Markus Eichner
- Maximilian I. Ruge (ORCID: https://orcid.org/0000-0003-0466-6646)
- Stefan Hunsche (ORCID: https://orcid.org/0000-0002-0059-1758)
- Nadine Sonntag
Institutions
- University Hospital Cologne (DE)
Publication Details
- Journal
- Journal of Applied Clinical Medical Physics
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1002/acm2.70318
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00