Knowledge‐based plan library‐guided adaptive proton stereotactic ablative radiotherapy (SABR) for localized prostate cancer
This study establishes the feasibility of a KB plan-driven adaptive proton SABR workflow for prostate cancer. By pre-generating motion-informed treatment plans and selecting the most optimal plan using ProKnow scoring, this framework ensures robust target coverage while substantially improving bladder and bladder neck sparing.
Authors
- Jun Zhou (ORCID: https://orcid.org/0000-0003-4799-8165)
- Zachary Diamond
- Keyur D Shah (ORCID: https://orcid.org/0000-0002-0886-655X)
- Pretesh Patel (ORCID: https://orcid.org/0000-0002-3522-1204)
- Vishal R. Dhere (ORCID: https://orcid.org/0000-0002-8364-7488)
- Hania Al‐Hallaq (ORCID: https://orcid.org/0000-0003-4274-6524)
- Anees Dhabaan (ORCID: https://orcid.org/0000-0002-6426-2443)
- Sagar A. Patel (ORCID: https://orcid.org/0000-0001-5174-2096)
- Duncan Bohannon
- Hamilton S. McGinnis
- Chih‐Wei Chang (ORCID: https://orcid.org/0000-0002-3818-4381)
- Adeel Zafar (ORCID: https://orcid.org/0000-0002-4826-7746)
- Xiaofeng Yang
Institutions
- Emory University (US)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1002/mp.70060
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00