Evaluation of a Retrieval-Augmented Generation Chatbot for Antimicrobial Resistance Research: Comparative Analysis of Large Language Models

A RAG-based chatbot can effectively support AMR research by delivering accurate, context-grounded, and scalable access to scientific literature. The comparative evaluation highlights trade-offs between performance, cost, and speed, guiding the selection of LLM architectures for clinical and research settings. Future work will focus on integrating language-specific embeddings and specialized domain agents to further enhance accuracy, adaptability, and clinical use.

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Publication Details

Journal
JMIR AI
Published
2025-10-24
DOI
https://doi.org/10.2196/83206
Primary Topic
Innovative Microfluidic and Catalytic Techniques Innovation
Type
article
Field-Weighted Citation Impact
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article

Evaluation of a Retrieval-Augmented Generation Chatbot for Antimicrobial Resistance Research: Comparative Analysis of Large Language Models

Óscar Escudero-Arnanz, Cristina Soguero-Ruíz, Manuel Eduardo Valero-Méndez, Noelia Sánchez-Ramos
JMIR AI
Innovative Microfluidic and Catalytic Techniques Innovation
article

Evaluation of a Retrieval-Augmented Generation Chatbot for Antimicrobial Resistance Research: Comparative Analysis of Large Language Models

Óscar Escudero-Arnanz, Cristina Soguero-Ruíz, Manuel Eduardo Valero-Méndez, Noelia Sánchez-Ramos
article en

Abstract

A RAG-based chatbot can effectively support AMR research by delivering accurate, context-grounded, and scalable access to scientific literature. The comparative evaluation highlights trade-offs between performance, cost, and speed, guiding the selection of LLM architectures for clinical and research settings. Future work will focus on integrating language-specific embeddings and specialized domain agents to further enhance accuracy, adaptability, and clinical use.

JMIR AIVol. 5
Universidad Rey Juan Carlos (ES)
Openalex Percentile: Top 70%
Innovative Microfluidic and Catalytic Techniques Innovation
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