Enhancing AI-based diabetic retinopathy screening in low- and middle-income countries with synthetic data
RetSyn presents an effective and scalable synthetic data framework that significantly enhances the robustness and generalizability of AI-based DR screening models in LMICs. By addressing the critical challenges posed by varying image quality and device characteristics, RetSyn facilitates more reliable deployment of AI diagnostics in underserved regions. Additionally, the release of the first publicly available paired smartphone-tabletop retinal image dataset will support further research into cross-device DR screening solutions.
Authors
- David Restrepo (ORCID: https://orcid.org/0000-0002-3789-1957)
- Michael Morley (ORCID: https://orcid.org/0000-0001-6373-7008)
- Luis Filipe Nakayama (ORCID: https://orcid.org/0000-0002-6847-6748)
- Chenwei Wu (ORCID: https://orcid.org/0009-0003-7178-1377)
- Zitao Shuai
- Zhengxu Tang
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Carleton College (US)
- University of Michigan (US)
Publication Details
- Journal
- Journal of Biomedical Informatics
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1016/j.jbi.2025.104938
- Citations
- 1
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.36