Fibrotic and vascular abnormalities quantified by an AI-based model are associated with outcomes in patients with idiopathic pulmonary fibrosis
LungQ allows to quantify interstitial and vascular lung features and their changes over time in a large cohort of patients with IPF. Imaging markers were negatively correlated with PFT at baseline and follow-ups were predictive of mortality confirming their potential as disease quantifiers. Further clinical validation is needed to specify the potential clinical use.
Authors
- Renaud Louis
- David A. Lynch (ORCID: https://orcid.org/0000-0002-6329-2325)
- Quentin Maloir (ORCID: https://orcid.org/0000-0003-2182-5426)
- Julien Guiot (ORCID: https://orcid.org/0000-0001-7800-1730)
- Benoit Ernst (ORCID: https://orcid.org/0000-0002-1096-049X)
- Jonne Engelberts
- Stephen M. Humphries (ORCID: https://orcid.org/0000-0002-5113-4530)
- Monique Henket (ORCID: https://orcid.org/0000-0001-9648-9645)
- Jean-Paul Charbonnier
Institutions
- University of Liège (BE)
- National Jewish Health (US)
- Centre Hospitalier Universitaire de Liège (BE)
- University of Colorado Denver (US)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1186/s12890-025-03949-7
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00