Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients

High-precision photon and particle radiotherapy achieved effective long-term control with favorable safety in high-grade meningiomas. Most adverse effects were mild and manageable, supporting the role of particle therapy in reducing selected late toxicities.

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Publication Details

Journal
Journal of Neuro-Oncology
Published
2025-10-24
DOI
https://doi.org/10.1007/s11060-025-05255-y
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients

Semi Harrabi, Klemens Zink, T Mohamed, Hilke Vorwerk et al.
Journal of Neuro-Oncology
Meningioma and schwannoma management
article

Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients

Semi Harrabi, Klemens Zink, T Mohamed, Hilke Vorwerk, Daniel Habermehl, Ahmed Gawish, Linda Agolli, Markus Schymalla, Sebastian Adeberg, Kerem Tuna Tas, Philipp Lishewski, Fatima Frosan Sheikhzadeh, Finja Svende Höft
article en

Abstract

High-precision photon and particle radiotherapy achieved effective long-term control with favorable safety in high-grade meningiomas. Most adverse effects were mild and manageable, supporting the role of particle therapy in reducing selected late toxicities.

Journal of Neuro-OncologyVol. 176(1)
Goethe University Frankfurt (DE), Philipps University of Marburg (DE), Justus-Liebig-Universität Gießen (DE), Heidelberg University (DE), Universitätsklinikum Gießen und Marburg (DE), University Hospital Heidelberg (DE), Heidelberger Institut für Radioonkologie (DE), University Hospital Frankfurt (DE), Technische Hochschule Mittelhessen (DE)
Openalex Percentile: Top 59%
Meningioma and schwannoma management
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