Postoperative Cognitive Alterations and Functional Brain Reorganization in Children With Middle Cranial Fossa Arachnoid Cysts: A Pilot fMRI Study
Microsurgical decompression of MFAC in children yields cognitive improvements and drives large-scale network reorganization, normalizing contralateral hyperactivation through cross-frequency modulation. These findings support surgical consideration even in minimally symptomatic cases, though further studies with larger cohorts are warranted.
Authors
- Wenjian Zheng (ORCID: https://orcid.org/0000-0001-5490-3852)
- Xueyi Guan (ORCID: https://orcid.org/0000-0002-5563-6669)
- Fan Xu (ORCID: https://orcid.org/0009-0001-2895-6798)
- Xu Han (ORCID: https://orcid.org/0000-0003-0723-3707)
- Jinfeng Wu (ORCID: https://orcid.org/0000-0001-8539-0973)
- Jian Gong (ORCID: https://orcid.org/0000-0003-3224-9997)
- Bohan Hu
- Jian-Wei Ni
- Huina Zhai
- Jie Wang (ORCID: https://orcid.org/0000-0003-4338-2873)
- Cuiling Hu
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- Hubei University of Arts and Science (CN)
- Songjiang District Central Hospital (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Neurosurgery
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1227/neu.0000000000003823
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.00