Infection and abduction loss predict equine laryngoplasty failure

BACKGROUND: Prosthetic laryngoplasty (PL) is the most common surgical treatment for recurrent laryngeal neuropathy (RLN) in horses. Post-operative complications may compromise outcomes, and the influence of breed and anaesthetic approach remains unclear. OBJECTIVES: To evaluate factors associated with surgical outcome at 3 months following PL, focusing on post-operative complications, anaesthetic modality and breed (particularly Iberian baroque breeds). STUDY DESIGN: Multicentre retrospective cohort study. METHODS: or Fisher's exact tests and Spearman correlation. Two binomial generalised linear mixed models, with surgeon as a random effect, evaluated pre/intra-operative predictors and post-operative prognostic factors. Level of significance p < 0.05. Surgical success was defined as the absence of respiratory noise and exercise intolerance at 3 months. RESULTS: Surgical success was achieved in 79.1% of cases. Complications occurred in 33.7% of horses and were negatively associated with treatment success (odds ratio [OR] 0.003; 95% confidence interval [CI] 0.000-0.052; p < 0.001). Major loss of arytenoid abduction (18.2%) and surgical site infection (SSI; 6.6%) were the only variables independently associated with reduced odds of treatment success in the post-operative model (OR 0.011; 95% CI 0.001-0.178; p = 0.001 and OR 0.046; 95% CI 0.004-0.559; p = 0.016, respectively). Breed was not associated with surgical outcome. MAIN LIMITATIONS: The retrospective multicentre design may introduce selection bias, variability in clinical practice and heterogeneous follow-up. CONCLUSIONS: Major loss of arytenoid abduction and SSI were the strongest predictors of failure, highlighting the importance of meticulous technique, preservation of arytenoid abduction and rigorous infection control to optimise outcomes after PL.