Genetic Variation in Background Mucosa Across Different Grades of Chronic Esophagitis

Regardless of LVLs grade, the background mucosa of patients with chronic esophagitis who already had ESCC or SD had already accumulated the same level of TP53 gene mutations. Even patients with LVLs grade B chronic esophagitis should undergo regular endoscopic examination for early detection of ESCC.

Authors

Institutions

Publication Details

Journal
Journal of Gastroenterology and Hepatology
Published
2025-10-24
DOI
https://doi.org/10.1111/jgh.70129
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Genetic Variation in Background Mucosa Across Different Grades of Chronic Esophagitis

Kenichiro Okimoto, Tomoaki Matsumura, Takashi Taida, Tsubasa Ishikawa et al.
Journal of Gastroenterology and Hepatology
Esophageal Cancer Research and Treatment
article

Genetic Variation in Background Mucosa Across Different Grades of Chronic Esophagitis

Kenichiro Okimoto, Tomoaki Matsumura, Takashi Taida, Tsubasa Ishikawa, Kenji Amemiya, Naoki Akizue, Kazuyuki Matsushita, Yosuke Hirotsu, Jun Kato, Motoi Nishimura, Hitoshi Mochizuki, Masao Omata, Tatsuya Kaneko, Yuki Ohta, Jun‐ichiro Ikeda, Takehisa Ohashi, Keisuke Matusaka, Akane Krosugi
article en

Abstract

Regardless of LVLs grade, the background mucosa of patients with chronic esophagitis who already had ESCC or SD had already accumulated the same level of TP53 gene mutations. Even patients with LVLs grade B chronic esophagitis should undergo regular endoscopic examination for early detection of ESCC.

Journal of Gastroenterology and HepatologyVol. 40(12)
Tokyo Medical University (JP), Chiba University (JP), Tokyo City University (JP), Chiba University Hospital (JP), Yamanashi Prefectural Central Hospital (JP)
Openalex Percentile: Top 52%
Esophageal Cancer Research and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.