Clinical study of wearable low-intensity pulsed ultrasound treatment in the improvement of executive function in obesity (the SLITE trial): protocol for a single -centre, double-blind, randomized controlled trial
This trial will be the first to evaluate LIPUS for enhancing executive function in individuals with obesity. By combining wearable ultrasound technology with neuroimaging assessments, the study is expected to provide novel evidence for the neuromodulatory role of LIPUS. The results may support the development of innovative, non-invasive strategies for obesity management and inform future clinical applications.
Authors
- Xi Xiong (ORCID: https://orcid.org/0000-0003-3882-5553)
- Tingyu Zhang (ORCID: https://orcid.org/0000-0002-3082-7506)
- Xue Xie
- Yuanyi Zheng (ORCID: https://orcid.org/0000-0002-1328-0641)
- Fengjing Liu (ORCID: https://orcid.org/0000-0002-3922-8788)
- Junnian Hao
- Chuanyu Zhong
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Sixth People's Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fnhum.2025.1698351
- Citations
- 2
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- National Natural Science Foundation of China
- Shanghai Jiao Tong University
- National Key Research and Development Program of China