Recurrence of neurogenic heterotopic ossification after surgical excision and preventive strategies: A systematic review and meta-analysis
This study found no significant differences in recurrence rates among treatment groups but noted fewer NHO recurrences with combined pharmacology and surgery in recent studies (after 2000), suggesting potential efficacy of postoperative pharmacotherapy for high-risk patients, though limitations like non-controlled studies and heterogeneity warrant caution.
Authors
- Reza Elahi (ORCID: https://orcid.org/0000-0001-9612-2587)
- Maryam Yousefiasl (ORCID: https://orcid.org/0000-0002-6995-5169)
- Majid Chalian (ORCID: https://orcid.org/0000-0001-8400-1593)
- Arash Azhideh (ORCID: https://orcid.org/0000-0001-9740-9766)
- Nicholas M. Hernandez (ORCID: https://orcid.org/0000-0003-0871-4465)
- Howard A. Chansky (ORCID: https://orcid.org/0000-0003-4650-424X)
- Sara Haseli
- Peyman Mirghaderi (ORCID: https://orcid.org/0000-0002-3522-8772)
- David Camacho (ORCID: https://orcid.org/0000-0002-0535-7450)
- Ali Nabipoor
Institutions
- Zanjan University of Medical Sciences (IR)
- University of Washington (US)
- Indiana University School of Medicine
Publication Details
- Journal
- Journal of Spinal Cord Medicine
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1080/10790268.2025.2571821
- Primary Topic
- Heterotopic Ossification and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00