When and why do children develop hyperglycemia during acute lymphoblastic leukemia therapy?
Hyperglycemia was a frequent early adverse event in pediatric acute lymphoblastic leukemia treatment, particularly among pubertal patients and those at high relapse risk. Despite its high incidence, hyperglycemia was not associated with worse clinical outcomes in this cohort. These findings underscore the importance of early identification and monitoring, particularly during high-risk treatment phases.
Authors
- Ana Virgínia Lopes de Sousa (ORCID: https://orcid.org/0000-0001-8479-6322)
- Angela Maria Spinola‐Castro (ORCID: https://orcid.org/0000-0003-1974-0925)
- Adriana Aparecida Siviero‐Miachon (ORCID: https://orcid.org/0000-0002-3001-0184)
- Lívia Cristina Oliveira E Silva (ORCID: https://orcid.org/0009-0009-8811-0784)
Institutions
- Support group for adolescents and children with cancer (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Revista da Associação Médica Brasileira
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1806-9282.20240953
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00