Impact of an antimicrobial stewardship bundle on the outcome of high-risk neutropenic patients with fever: a pre-post study
The AMS bundle led to a shift towards narrower-spectrum antibiotics, and reduced treatment duration and overall antibiotic use without a significant impact on the primary safety outcome. The intervention was accompanied by a declining trend in candidaemia incidence.
Authors
- Jarom Heijmans (ORCID: https://orcid.org/0000-0001-9615-7851)
- Suzanne M E Kuijpers (ORCID: https://orcid.org/0000-0002-6821-0405)
- Jan M. Prins (ORCID: https://orcid.org/0000-0002-5415-8933)
- Rogier P. Schade (ORCID: https://orcid.org/0000-0002-9487-4467)
- Jara R. de la Court (ORCID: https://orcid.org/0000-0002-5389-2159)
- Kim Sigaloff (ORCID: https://orcid.org/0000-0001-6754-3809)
Institutions
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Institute of Infection and Immunity (CA)
- Amsterdam University of Applied Sciences (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-09-03
- DOI
- https://doi.org/10.1093/jacamr/dlaf191
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amsterdam University Medical Centers