Diagnosis of Trypanosoma cruzi infection in Mexican populations: current conventional serology lacks adequate sensitivity and specificity
The current study provides evidence for inadequate diagnostic performance of conventional serological tests and the need to develop appropriate antigenic tools and use molecular testing of seronegatives to ascertain absence of infection.
Authors
- Gilberto Sánchez‐González (ORCID: https://orcid.org/0000-0002-4322-0084)
- Monica Reyes-Romero
- Angélica Pech‐May (ORCID: https://orcid.org/0000-0003-4942-7788)
- Sleidher Gutiérrez (ORCID: https://orcid.org/0000-0002-0820-7810)
- Janine M. Ramsey (ORCID: https://orcid.org/0000-0002-5950-0830)
- Ezequiel Tun-Ku
- Kenia Escobedo-López
- Alejandro G. Schijman (ORCID: https://orcid.org/0000-0001-9805-3415)
- Keynes de la Cruz‐Félix (ORCID: https://orcid.org/0000-0002-6123-3583)
- Margarita Virgen-Cuevas
Institutions
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Instituto Nacional de Salud Pública (MX)
- Instituto de Investigación de Enfermedades Raras (ES)
- Experimental Medicine and Biology Institute (AR)
Publication Details
- Journal
- Memórias do Instituto Oswaldo Cruz
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/0074-02760240224
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00