TIMP4 as a Potential Complementary Biomarker and Therapeutic Target in Membranous Nephropathy: A Multi-Omics Investigation with Clinical Validation
This study suggests TIMP4 may serve as a novel complementary biomarker and potential therapeutic target in MN. Systematic integration of multi-omics and clinical data provides promising insights for future drug development and mechanistic exploration.
Authors
- Juntao Ran (ORCID: https://orcid.org/0000-0002-4240-8579)
- Yan‐Jia Luo (ORCID: https://orcid.org/0000-0002-1288-438X)
- Qi Huang (ORCID: https://orcid.org/0000-0001-6308-0130)
- Qiyuan Hu (ORCID: https://orcid.org/0000-0002-3326-6441)
- Gang Wang (ORCID: https://orcid.org/0000-0003-3296-3015)
- Yuting Wang (ORCID: https://orcid.org/0000-0001-6176-2381)
- Rui Zhao (ORCID: https://orcid.org/0000-0002-6602-6583)
- Qingsong Chen (ORCID: https://orcid.org/0009-0008-1142-6329)
- Jiayun Li (ORCID: https://orcid.org/0000-0001-7800-5686)
- Gong Yu
- Xiaohui Liao (ORCID: https://orcid.org/0000-0002-2329-0456)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/jir.s545422
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chongqing Medical University
- Centre Scientifique et Technique du Bâtiment