Long-term effects of simulated microgravity in the central nervous system of rhesus monkeys: a voxel-wise multimodal MRI study
Using multimodality MRI, this study indicated that simulated microgravity might cause widespread abnormalities through neuroplasticity, especially in brain regions in charge of visuospatial awareness and voluntary motion. There may exist a complex functional compensation between the reconstruction of gray and white matter and the rearrangement of neural connections.
Authors
- Rui Li (ORCID: https://orcid.org/0009-0007-0894-1947)
- Yuan‐Xiang Tao (ORCID: https://orcid.org/0000-0003-1777-3272)
- Xuan Xuan
- Da-Yong Lu (ORCID: https://orcid.org/0000-0002-9026-8558)
- Kai Xu (ORCID: https://orcid.org/0000-0002-7776-2455)
- Suping Zhao
- Chenhao Zhao (ORCID: https://orcid.org/0000-0001-7256-6714)
- Yanli Liu (ORCID: https://orcid.org/0000-0003-0886-8907)
- Li Liu (ORCID: https://orcid.org/0000-0002-2011-2873)
- Xiaoyun Zhang (ORCID: https://orcid.org/0000-0003-0349-1127)
- Yawei Zeng (ORCID: https://orcid.org/0000-0002-0197-3192)
- Juan Du (ORCID: https://orcid.org/0000-0002-4194-4652)
- Dong Zheng (ORCID: https://orcid.org/0000-0003-1086-0621)
- J. Wang (ORCID: https://orcid.org/0009-0002-0724-4385)
- Jigong Wu (ORCID: https://orcid.org/0000-0002-3394-1507)
Institutions
- Anhui Medical University (CN)
- Chinese PLA General Hospital (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.3389/fphys.2025.1634366
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00