High-throughput and Efficient Assay for Central Nervous System Infection with Targeted Nanopore Sequencing Technology
Our tNPS as a culture-independent diagnostic assay offered enhanced efficiency, high-throughput capability, and an expanded pathogen detection spectrum, facilitating potential implementation in molecular diagnosis of CNS infection.
Authors
- Zhanguo Chen (ORCID: https://orcid.org/0000-0002-6664-7750)
- Chuyuan Ye
- Guangxin Xiang
- Xi Jiang (ORCID: https://orcid.org/0000-0003-3711-0847)
- Xiaoqun Zheng (ORCID: https://orcid.org/0000-0002-9816-4833)
- Feng Xu (ORCID: https://orcid.org/0000-0001-6372-635X)
- Jian Yu
- Haitao Ren
- Zhongdong Lin
- Lanni Wang
- Meiyun Wang (ORCID: https://orcid.org/0000-0002-7163-2617)
- Ye Shi
- Man Zou
- Yang Geng (ORCID: https://orcid.org/0009-0000-4651-4101)
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Infection and Drug Resistance
- Published
- 2025-10-01
- DOI
- https://doi.org/10.2147/idr.s540638
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wenzhou Medical University
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province