Association Between Obstructive Sleep Apnea and Prostate Cancer: NHANES and the Mendelian Randomization Study

The findings indicate that while there is no significant association between OSA and prostate cancer in the overall analysis, a significant negative correlation exists in the younger population. The lack of significant association in the Mendelian randomization analysis may be due to the inability to perform age stratification. Further prospective studies and mechanistic research are needed to better understand the biological mechanisms underlying this association.

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Publication Details

Journal
Nature and Science of Sleep
Published
2025-10-01
DOI
https://doi.org/10.2147/nss.s496540
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Obstructive Sleep Apnea and Prostate Cancer: NHANES and the Mendelian Randomization Study

Binglei Jiang, Ping-Yu Zhu, Erhao Bao, Li Wang et al.
Nature and Science of Sleep
Genetic Associations and Epidemiology
article

Association Between Obstructive Sleep Apnea and Prostate Cancer: NHANES and the Mendelian Randomization Study

Binglei Jiang, Ping-Yu Zhu, Erhao Bao, Li Wang, Ying Liu, Long Xia
article en

Abstract

The findings indicate that while there is no significant association between OSA and prostate cancer in the overall analysis, a significant negative correlation exists in the younger population. The lack of significant association in the Mendelian randomization analysis may be due to the inability to perform age stratification. Further prospective studies and mechanistic research are needed to better understand the biological mechanisms underlying this association.

Nature and Science of SleepVol. Volume 17
North Sichuan Medical University (CN), Fourth People's Hospital of Sichuan Province (CN), Affiliated Hospital of North Sichuan Medical College (CN), Lanzhou University Second Hospital (CN), Zigong First People's Hospital (CN), Dazhou Central Hospital (CN), Lanzhou University (CN)
Openalex Percentile: Top 67%
Genetic Associations and Epidemiology
DOIOpen Access PDFOpenAlex
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Association Between Obstructive Sleep Apnea and Prostate Cancer: NHANES and the Mendelian Randomization Study — Binglei Jiang, Ping-Yu Zhu, et al. · Nature and Science of Sleep (2025) | TGRS Research Map | TGRS