High predicted cardiac event risk in youth with obesity and type 2 diabetes: a pooled cohort analysis
Y-T2D had an estimated 4.5- and 1.4-times higher risk for predicted CVD events compared to Lean and OW/OB peers, respectively. Lipoprotein and inflammatory risk-enhancing factors may help stratify and guide primary prevention strategies in high-risk AYA.
Authors
- Stephanie T. Chung (ORCID: https://orcid.org/0000-0001-6989-0417)
- Geethika Thota (ORCID: https://orcid.org/0000-0003-0438-8498)
- Sheela N. Magge (ORCID: https://orcid.org/0000-0002-0949-4399)
- Maureen Sampson
- Marissa Lightbourne (ORCID: https://orcid.org/0000-0001-5498-0452)
- Faith Davis (ORCID: https://orcid.org/0000-0001-8887-9870)
- Noemi Malandrino (ORCID: https://orcid.org/0000-0001-5587-1127)
- Jack Adam Yanovski (ORCID: https://orcid.org/0000-0001-8542-1637)
- SAMSON L. CANTOR
- LILIAN MABUNDO
- Sophia B. Glaros
- Alan T. Remaley (ORCID: https://orcid.org/0000-0003-2473-5549)
- NATALIE A. MACHERET
- ILA N. KACKER
Institutions
- Johns Hopkins University (US)
- National Institute of Diabetes and Digestive and Kidney Diseases (US)
- National Heart, Lung, and Blood Institute (US)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1186/s12933-025-02951-x
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 0.00