Clinical outcomes of norepinephrine–phenylephrine vs. norepinephrine–vasopressin in septic shock: a retrospective cohort study
In septic shock patients, NE-PE may be associated with reduced in-hospital mortality compared to NE-VP, especially among patients aged <65 years or those without hypertension. The Shock Index may serve as a valuable indicator for selecting a secondary vasopressor during vasopressor escalation.
Authors
- Yihan Ding
- Xiaohang Song
- Xiner Zhang
- Weicai Huang (ORCID: https://orcid.org/0000-0002-8046-1151)
- Jingsong Chen (ORCID: https://orcid.org/0000-0002-3152-8030)
- Yi Dong (ORCID: https://orcid.org/0000-0002-0212-1477)
- Kai Zhang (ORCID: https://orcid.org/0009-0005-1294-2876)
- Yun Guo (ORCID: https://orcid.org/0000-0003-1563-7568)
- Yanan Tang (ORCID: https://orcid.org/0000-0001-7861-5900)
- Xiao Yang (ORCID: https://orcid.org/0009-0000-9941-9503)
- Guangming Wen
- Xuetao Lei
Institutions
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Zhongshan People's Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1097/js9.0000000000003722
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00