Decoding the human tongue of light chain amyloidosis in three dimensions (3D): three-dimensional pathological visualization drives early and precise screening of suspected cases

CUBIC-based 3D imaging enables detailed visualization and quantification of amyloid-associated microstructural changes in tongue tissue, providing deeper insight into disease mechanisms and serving as a valuable complement to conventional histopathology for enhancing early diagnostic accuracy in AL amyloidosis.

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Publication Details

Journal
BMC Oral Health
Published
2025-10-24
DOI
https://doi.org/10.1186/s12903-025-06939-7
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
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article

Decoding the human tongue of light chain amyloidosis in three dimensions (3D): three-dimensional pathological visualization drives early and precise screening of suspected cases

Zuomin Wang, Liqiong Wu, Yongcun Qu, Jing Chen et al.
BMC Oral Health
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Decoding the human tongue of light chain amyloidosis in three dimensions (3D): three-dimensional pathological visualization drives early and precise screening of suspected cases

Zuomin Wang, Liqiong Wu, Yongcun Qu, Jing Chen, Zheng Zhang, Fang Hong Sun, Xiaoli Gao, Si Xu, Zhiqiang Liu
article en

Abstract

CUBIC-based 3D imaging enables detailed visualization and quantification of amyloid-associated microstructural changes in tongue tissue, providing deeper insight into disease mechanisms and serving as a valuable complement to conventional histopathology for enhancing early diagnostic accuracy in AL amyloidosis.

BMC Oral HealthVol. 25(1)
Capital Medical University (CN), Beijing Chao-Yang Hospital, Capital Medical University (CN), Beijing Chang'an Integrated Traditional Chinese and Western Medicine Hospital (CN), Capital University of Physical Education and Sports (CN), Beijing Chaoyang Emergency Medical Center (CN)
Openalex Percentile: Top 73%
Amyloidosis: Diagnosis, Treatment, Outcomes
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Decoding the human tongue of light chain amyloidosis in three dimensions (3D): three-dimensional pathological visualization drives early and precise screening of suspected cases — Zuomin Wang, Liqiong Wu, et al. · BMC Oral Health (2025) | TGRS Research Map | TGRS